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I don’t think I can stomach the plain YuGiOh simulators from back then. It’s quite boring, especially after having played the modern game. I do think it’s worth getting at a dicount for the weirder ones though.
However, I’d buy a collection of all their weird 3D games in heartbeat. Forgotten Memories, Kingdom of Illusion, Duelists of the Roses and so on.
My vote goes to Dragon Quest. Early gaming was dominated by JRPGs like DQ, Final Fantasy or Chrono Trigger. Pretty much every modern game has RPG elements. While there are earlier RPGs, DQ popularized them and invented the JRPG.
Of course, literally speaking, the first game ever is the most influential - therefore Tennis for Two.